Three-dimensional dosimetry imaging of I-125 plaque for eye cancer treatment

نویسندگان

  • Michael Weaver
  • Janette P. Green
  • Marco Petasecca
  • Michael L. Lerch
  • Dean L. Cutajar
  • D. Franklin
  • J Jakubek
  • Martin G. Carolan
  • Anatoly B. Rosenfeld
  • M. Weaver
  • J. Green
  • M. Petasecca
  • M.L.F. Lerch
  • D. Cutajar
  • J. Jakubek
  • M. G. Carolan
  • M. Conway
  • S. Pospisil
  • T. Kron
  • P. Metcalfe
  • M. Zaider
  • A. B. Rosenfeld
چکیده

Treatment of ocular cancers using eye plaque brachytherapy is now an established medical procedure. However, current QA for these eye plaques is quite rudimentary, limiting the opportunities for precise pretumour plaque customisation. This paper proposes and experimentally validates a new technique for imaging of eye plaque dose distributions using a high-resolution pixelated silicon detector. Results are presented demonstrating the 2D and 3D isodose surfaces produced using experimental data collected using this method.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Outcomes of medium choroidal melanomas treated with ruthenium brachytherapy guided by three-dimensional pretreatment modeling.

PURPOSE The Collaborative Ocular Melanoma Study (COMS) established iodine-125 (I-125) plaque brachytherapy for eye preserving treatment of medium-sized choroidal melanomas in the United States. Eye Physics I-125 plaque treatment modeled with Plaque Simulator (PS) software yields similar results to COMS. Herein, we report results from a series of 15 patients treated with ruthenium-106 (Ru-106) p...

متن کامل

Monte Carlo Simulation for Treatment Planning Optimization of the COMS and USC Eye Plaques Using the MCNP4C Code

Introduction: Ophthalmic plaque radiotherapy using I-125 radioactive seeds in removable episcleral plaques is often used in management of ophthalmic tumors. Radioactive seeds are fixed in a gold bowl-shaped plaque and the plaque is sutured to the scleral surface corresponding to the base of the intraocular tumor. This treatment allows for a localized radiation dose delivery to the tumor with a ...

متن کامل

Episcleral eye plaque dosimetry comparison for the Eye Physics EP917 using Plaque Simulator and Monte Carlo simulation

This work is a comparative study of the dosimetry calculated by Plaque Simulator, a treatment planning system for eye plaque brachytherapy, to the dosimetry calculated using Monte Carlo simulation for an Eye Physics model EP917 eye plaque. Monte Carlo (MC) simulation using MCNPX 2.7 was used to calculate the central axis dose in water for an EP917 eye plaque fully loaded with 17 IsoAid Advantag...

متن کامل

Monte Carlo dosimetry of the eye plaque design used at the St. Erik Eye Hospital for (125)I brachytherapy.

PURPOSE At St. Erik Eye Hospital in Stockholm, Sweden, ocular tumors of apical height above 6 mm are treated with brachytherapy, using iodine-125 seeds attached to a gold alloy plaque while the treatment planning is performed assuming homogeneous water surroundings. The aim of this work was to investigate the dose-modifying effects of the plaque and the seed fixating silicone rubber glue. MET...

متن کامل

Three-dimensional gel dosimetry for dose volume histogram verification in compensator-based IMRT

Background: Some tissues in human body are radiobiologically different from water and these inhomogeneity must be considered in dose calculation in order to achieve an accurate dose delivery. Dose verification in complex radiation therapy techniques, such as intensity‐modulated radiation therapy (IMRT) calls for volumetric, tissue equivalent and energy independent dosimeter. The purpose of this...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2016